General Information

  • ID:  hor003235
  • Uniprot ID:  NA
  • Protein name:  Met-enkephalin-Arg-Gly-Leu
  • Gene name:  NA
  • Organism:  Spea multiplicatus
  • Family:  Opioid neuropeptide precursor family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  YGGFMRNY
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003235_AF2.pdbhor003235_ESM.pdb

Physical Information

Mass: 113216 Formula: C46H62N12O12S
Absent amino acids: ACDEHIKLPQSTVW Common amino acids: GY
pI: 9.17 Basic residues: 1
Polar residues: 5 Hydrophobic residues: 1
Hydrophobicity: -83.75 Boman Index: -1463
Half-Life: 2.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: 2 min Aliphatic Index 0
Instability Index: 1956.25 Extinction Coefficient cystines: 2980
Absorbance 280nm: 425.71

Literature

  • PubMed ID:  10793214
  • Title:  Organization of proenkephalin in amphibians: cloning of a proenkephalin cDNA from the brain of the anuran amphibian, Spea multiplicatus